There can be a variety of reasons for the conservation of sequence (including correlations between 'distant' regions), but the importance to structure and function, and functional linkage between them, underlie such correlations.
Bitfield definitions are nominally CPU dependent (but so is everything) but also genuinely endianness dependent.Data representation and function linkage are aspects of a formal standard called Application Binary Interface (ABI), and the chapter describes the conventions used in the ABI, sometimes called o32.
The GCNs here are gene function linkage networks [11], [12], [40], [41].
The Matlab functions, linkage and dendrogram, are employed to determine the number of clusters.
The crotonase superfamily sequences and annotations came from the 1,330 publicly available sequences in this superfamily in the Structure-Function Linkage Database[40] on Jan . 16 2008 from http://sfld.rbvi.ucsf.edu.ucsf.edu
Candidate genes can be identified by different means, including function, linkage, and genome-wide association.
The FineFams have been benchmarked against the Structure Function Linkage Database (SFLD) [25].
Most of the reported genes were chosen because of their known functions, linkage evidence or both.
A very useful starting point may be the structure-function linkage database ; http://sfld.rbvi.ucsf.edu/django/.
Left fusiform gyrus regions are also activated in metabolic studies contrasting words and visual control stimuli, and this area has been termed the Visual Word Form Area [ 7, 42], suggesting a structure-function linkage between this region and early cognitive perceptual processes proposed in models of word recognition [ 38].
