Development of OSCC involves perturbed regulation of genes functioning in interaction with the external environment, such as those functioning in cell adhesion and encoding components of the extra-cellular matrix (Figure 3a,e,f).
Clinicaltrials.gov ID NCT01457300 The main goal of rehabilitation is to achieve optimal functioning in interaction with the environment [ 1].
Rehabilitation is defined as "a set of measures that assist individuals, who experience or are likely to experience disability, to achieve and maintain optimum functioning in interaction with their environments" [ 4].
Rehabilitation – defined by the World Health Organization (WHO) as "a set of measures that assist individuals who experience or are likely to experience disability to achieve and maintain optimal functioning in interaction with their environment" [ 1] [p.96] – is a major strategy that addresses both the needs and rights of persons with impairments [ 6].
Unlike, for example, the lexical Big Five tradition of personality research, social-cognitive theories are concerned fundamentally with mental structures and dynamics that causally contribute to personality functioning and coherence, and with understanding how these cognitive and affective systems develop and function in interaction with the social environment.
Some of the αCTD residues required for UP element contact might also function in its interaction with Spx, and thus, may not be available for Spx-αCTD Spx-αCTDformation.
The results herein imply that these motifs function in protein/protein interaction since mutation of the ZFs or elimination of the OB fold affect editosome structural integrity.
This gene set is comprised of proteins that function in the interaction of cells with extracellular matrix, including integrins (ITGB1, ITGB5), collagens (COL1A1, COL1A2, COL5A1, COL6A2), glycoproteins (FN1, THBS2, SDC1), and other cell-surface-associated components.
These genes function in cell interaction, attachment, and motility.
Because the insertion in PPO1 homologs is rich in hydrophilic residues, this region may function in intermolecular interaction.
Our study supports the hypothesis that DNA secondary structures are important units that function in the interaction between proteins and genomic DNA sequences.
