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Our analysis reveals that multi-parametric profiling in a complex tissue yields functional maps with a resolution similar to genetic interaction-based profiling in unicellular eukaryotes pinpointing subunits of macromolecular complexes and components functioning in common cellular processes.
Because of this complexity, our understanding of the genes functioning in common wheat grain development is still incomplete, which is not conducive for effectively improving the yield and end-use traits of this important crop.
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Major unresolved issues include: how does a GATA factor selectively utilize diverse coregulators; do distinct epigenetic landscapes and nuclear microenvironments of target genes dictate coregulator requirements; and do gene cohorts controlled by a common coregulator ensemble function in common pathways.
New methods that efficiently assess the degree of cognitive function in common marmosets are needed in order to establish their suitability as non-human primate models of higher brain function disorders.
Like animal phagocytes, it engulfs bacteria by phagocytosis mainly through Toll-like receptors, and it has other biological functions in common with macrophages.
Additional proteins, identified using complementary biological/experimental systems, have functions in common with representatives in the PD-proteome.
According to this hypothesis, RBPs with important cellular functions co-regulate the expression of gene transcripts that function in common biochemical pathways or are present in common macromolecular structures.
When a gene without known function is associated with some genes that have a function in common, then it is natural to hypothesize that the same function can be attributed to that gene.
This increase may reflect methodological issues in generating OG relationships with such a divergent plant species, or the possibility that many of the C. reinhardtii FBX loci have either algal-specific functions, have functions in common within land plants but have significantly diverged sequences, or have diverged enough to become inactive.
For example, if two different sequences G1 and G2 of length 100 amino acids differ at only 20 percent of their amino acids, their respective neighborhoods of radius five (which correspond to sequences differing from them in no more than five percent of their amino acids) have merely 50 percent of their functions in common (Figure 3b).
These are the functions in common to all family members.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com