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We performed loss-of-function experiments for cited3 to investigate its functional role during development.
The gain-of-function experiments under discussion this week pose a reputational risk to the global biomedical research enterprise.
The modified pathogens created through so-called 'gain-of-function' experiments could, if accidentally released from labs or deliberately misused, cause man-made pandemics.
"Gain-of-function experiments are almost always loss-of-function experiments for another property.
Cellular function experiments showed that IGF-1 promoted PVAC proliferation, adhesion, and migration.
Gain-of-function experiments show that the presynaptic dose of DVAP-33A tightly modulates the number of synaptic boutons.
Small RNA interference transfection was used to study the function experiments in human 293T and SK-N-BE cell lines.
Additionally, our loss-of-function experiments -through Fgf8 siRNA electroporation- showed an increase of miR-133 expression.
Gain-of-function experiments can therefore have quite opposing results, depending on the time of gene activation.
In 2014 the U.S. government decided to cease funding these so-called "gain of function" experiments.
His highly conceptual 2001 album, Bodily Functions, experiments with sounds produced by body parts.
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CEO of Professional Science Editing for Scientists @ prosciediting.com