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Regarding the basis of cognitive functioning, evidence has been forthcoming in recent years of differences in brain structure between bipolar patients and healthy individuals, as well as changes over time in patients.
Unfortunately, while recent trials or observational studies have shown that early (neonatal) diagnosis and treatment results in improvements in nutritional status, height and weight, and cognitive functioning, evidence about the long-term impact of early diagnosis on lung function (and therefore mortality) remains uncertain [ 24- 28].
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Within this set of functions, evidence indicates that metabolic rate is the primary process.
While some anatomical changes enable the emergence of new functions, evidence also points to the importance of resting state oscillations in sculpting neural architecture during development.
Betatrophin has been shown to induce β-cell proliferation in a mouse model of insulin resistance on the basis of gain-of-function evidence derived from over-expression of betatrophin in the mouse liver (Yi et al., 2013).
This result reflects the idea that, according to an evidential support function, evidence claims are not "simply likely" to a certain degree on their own, independently of what any hypothesis has to say.
Function evidence for the role of Group 5 or Group 12 genes in plants is limited.
Data included epidemiologic and ventilatory factors, LV/RV function, evidence of RV restriction and pulmonary hemodynamics.
Gain-of-function evidence does suggest that there is some class specificity in biological functions, as only class I ETS DBDs are found in cancer-associated fusion proteins.
And while some snoRNAs may display only non-traditional functions, evidence is also accumulating of a subset of snoRNAs showing duality in their function.
For the cognitive function, evidence from previous studies has indicated that cognitive function begins to decline from the age of 50 and accelerates after age 65 [ 4].
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