Indeed, Rnt1p natural cleavage products possess the features necessary to function as guide RNAs.
They function as guide molecules in post-transcriptional gene regulation by base-pairing with the target mRNAs, usually in the 3' untranslated regions (UTRs), or, in a few cases, with target sites in the coding regions [2].
SnoRNAs usually function as guide RNAs to direct sequence-specific modifications of the targeted RNA.
MicroRNAs (miRNAs), small noncoding RNA molecules, are endogenous post-transcriptional regulators that function as guide molecules, pairing with partially or fully complementary motifs in 3′UTRs of their target mRNAs [1].
Given the significant correlation between pulmonary coagulation and pulmonary levels of suPAR, it will be interesting to investigate in future studies whether suPAR can possibly function as guide for local anticoagulant therapy.
Among these, small nucleolar RNAs (snoRNAs) are molecules of 60 300 nucleotides in length that function as guide RNAs for the post-transcriptional methylation and/or pseudouridylation of ribosomal RNAs.
They commonly have large landing surfaces and "tails" produced from the flower parts, which function as guides.
Following lesions of peripheral nerves, Schwann cells (SCs) reorganize to form longitudinal bands of Büngner (boB) which function as guides for regrowing axons.
They have made major strides both in documenting the historical development of the Zen school in East Asia and in understanding the religious and cultural contexts within which Zen literature, such as public cases, functioned as guides to spiritual truth.
But at the Museo Sveviano -- a modest collection of mementos and vintage photographs housed on the second floor of the musty, fabulously old-fashioned public library -- you can pick up a map of the places where Svevo lived and wrote the bittersweet novels that themselves function as guides to this moody and beautiful port city on the Adriatic.
The ledgers originally functioned as guides to salvation for twelfth-century Taoists and Buddhists, but Brokaw shows how the literati of turbulent sixteenth-century China began to use them as aids in the struggle for official status through civil service examinations.
