Sentence examples for functioning as a quality control from inspiring English sources
Autophagy can also selectively remove damaged or superfluous organelles, protein aggregates or invading pathogens, functioning as a quality control system.
In oocytes, TAp63 α is responsible for DNA damage-induced apoptosis, therefore functioning as a quality control factor in the female germline.
The ER functions as a quality control organelle and prevents misfolded proteins from traversing the secretory pathway [15].
The nuclear Rai1 protein is known to function as a endonuclease that can cleave near the 5′ ends of mRNAs, and this has been suggested to function as a quality control mechanism for mRNA capping (Jiao et al. 2010).
That NMD functions as a quality control mechanism tentatively suggested involvement of this particular RNA surveillance process in both the initiation and progression of neurodegenerative diseases and in treatment-induced modifications of disease symptoms.
This process of organellar protein turnover is reminiscent of endoplasmic reticulum associated degradation (ERAD), which functions both as a quality control and a regulatory pathway for ER proteins [13], [14].
In oocytes, TAp63 α expresses at relatively higher levels and functions as a quality control factor in the female germline, upon genotoxic stress [ 21– 23].
Recent studies have extended this view, indicating that NMD can function beyond a quality control mechanism, to serve as a mechanism for regulating gene expression disability (Huang and Wilkinson, 2012).
Therefore, it has been suggested that UBE3A also functions as a cellular quality control ubiquitin ligase.
Our observations that Rsp5 and the ART adaptor network are critical mediators of the heat-induced endocytic response suggested that these proteins may function as a critical quality control mechanism at the PM.
Once the raw data has been loaded into R and a "qPCRBatch" object has been generated, the distribution of Cq values for each sample can be compared in a pair-wise manner, using the pairs function or the mva.pairs function from the affy package [ 25] as a quality control step to identify outlying samples.
