Here, it functions as trigger for a safeguard mechanism that closes the binding site as soon as the ligand is lost.
And immunological abnormalities or infection may function as triggers of this neuralgia, because the neuralgia usually recurred while they were feeling fatigued or had a common cold.
Thus, throughout surgery deviations from standards or previously established plans can function as triggers to adapt the usual coordination strategy.
It was shown to be a major virulence factor in L. monocytogenes presumably functioning as triggering engulfment of the bacterium after specifically interacting with cell-surface receptors [ 25].
For ABC transporters, such a charge-induced conformational change may function as a trigger for releasing ΔGE, by lowering the transition-state energy barrier from CIn to COut.
This mechanism may be relevant to cocaine abuse in the context of extracellular matrix remodeling, in that a cocaine induced reset of pacemaker activity might be an underlying activity dependent metaplasticity that functions as a trigger for the consolidation or adaptive generalization of memories of an intense euphoria.
Thus, poor school achievement might function as a trigger for alterations in the causal pathway of genetic and environmental factors underlying neurobiological changes leading to mental disorders.
Collectively, these results emphasize that reversible phosphorylation may function as a trigger to induce or disrupt α-helix, depending on the position of the phosphorylation site within an α-helix.
While RBC necroptosis shared many molecular steps with canonical necroptosis pathways, it was distinct from eryptosis, a RBC-specific programmed cell death (PCD) that functions as a trigger for RBC clearance by macrophages.
The observation of an internal substrate binding site by X-ray crystallography has also helped to resolve the paradox since it suggests that substrate binding may function as a trigger for the switch from globin to peroxidase function by its strong interaction with the heme Fe.
(Subsequent work has shown that kainate receptors may function as the induction trigger at these synapses (Bortolotto et al., 1999)).
