These devices can encode genetic circuits that function analogously to their electronic counterparts.
Homology modeling suggests that a proline residue may function analogously to tryptophan in this particular position.
Cranial vault and facial sutures interpose between mineralized bones of the skull, and may function analogously to appendicular and cranial base growth plates.
The first tungsten-requiring enzyme to be discovered also requires selenium, and in this case the tungsten-selenium pair may function analogously to the molybdenum-sulfur pairing of some molybdenum cofactor-requiring enzymes.
Such a hypothetical nucleator would function analogously to the actin nucleating complex Arp2/3, which becomes activated on binding to an existing actin filament [6].
RuvC is not conserved in eukaryotes, but structure-specific nucleases, which have the ability to resolve HJs and may function analogously, have been identified.
Many of the regulatory trends we observed are more pronounced for gene-specific RBPs, i.e., those we predict to function analogously to TFs.
Conserved residues in alignments of NifH-like sequences with NifH sequences show that 4Fe-4S iron sulfur cluster-ligating cysteines and the P-loop/MgATP binding motif are invariant, suggesting that these proteins may function analogously to dinitrogenase reductase.
Hence, this N-terminal region is likely to contain at least one distinct globular domain, which might nevertheless function analogously to the N-terminal domains in the classical PIWI proteins in mediating additional nucleic acid contacts (see Figure 2B).
Our third hypothesis posits that lipophilic camptothecin may accumulate in the fat body (Zijlstra and Vogel 1988), which functions analogously to the liver in fruit flies and other insects (Buchon et al. 2009; Yang et al. 2007).
Cas proteins share functional similarity with proteins involved in eukaryotic RNA interference systems and, hence, it has been hypothesized that spacers function analogously to small interfering RNAs (Makarova et al., 2006).
