Sentence examples for functionally partner from inspiring English sources

Finally, we also tested the relative sensitivity of the five lines to γ-irradiation, since wild-type BRD4 is known to functionally partner with p53 (Wu et al, 2013) and have a role in insulating chromatin from the effects of DNA damage (Floyd et al, 2013), and NMC patients respond reasonably well to radiotherapy (Bauer et al, 2012).

Another intriguing example is the responsive backup circuit of genetic redundancy, in which any problem that reduces the stability of the activator is buffered by a functionally redundant partner to guarantee a robust output72,73,74.

The average shortest path length and betweenness centrality of functional partners in the clusters are calculated and they are functionally enriched with the Gene Ontology (GO) terms with a p-value cut-off ≤ 0.05.

We further observed other biological functions shared by pfcrt partners in both CQR and CQS, including heme biosynthesis and lipoamide biosynthesis, for which distinct but functionally related genes were identified as both CQR and CQS pfcrt functional partners.

Compensatory evolution was only partly limited to the known functionally interacting partners of the deleted gene.

We queried GAP with 306 known autism genes from the SFARI human gene module, and retrieved all functionally interacting partners predicted by it whose interaction p-values are less than 0.05.

Eigen and Schuster (1978) (part B) considered functionally cooperating partners belonging to different lineages to be the only possible solution to the problem of integrating more information in a system (i.e., the hypercycle).

In addition, figure 5 shows that the numbers of these functional diversity proxies for the epistatic-interaction partners of duplicate gene pairs are all positively correlated with the level of sequence divergence between these gene pairs, indicating that gene duplication also contributed to the evolution of gene pleiotropy by acquiring epistatic interactions with functionally versatile partners.

The present study was initiated as an approach to discovering the functionally relevant interaction partners of PrPC.

IsomiRs are tissue-specific and functionally active cooperative partners of canonical miRNAs (Cloonan et al. 2012).

The functionally obligate heterodimeric partners ARP7 and ARP9, the two ARPs restricted to fungi so far [ 18], are not present.