Sentence examples for functionally optimal from inspiring English sources

Our algorithm considers the optimization of two different objectives: On one hand a functionally optimal and thermodynamically feasible flux distribution is demanded an on the other hand the calculated metabolite concentrations are required to deviate as little as possible from set-point values prescribed on the basis of biochemical knowledge.

We are specifically interested in answering two questions: first, what cellular and molecular mechanisms cause young synapses to be stabilized at one position in the brain after an early period of exuberant projections where tentative contacts are made and broken before functionally optimal connections are formed?

Interestingly, [13] supposed a narrow functionally optimal range of dopaminergic transmission in the prefrontal target regions of MDT.

Furthermore, Turrigiano and colleagues show that this capacity of microglia is involved in homeostatic synaptic scaling, an adaptive response of brain directed toward tuning neural circuit activity to a functionally optimal state [14].

The conservation mode of isochore evolution was originally explained by "negative selection acting at a regional (isochore) level to eliminate any strong deviation from the presumably functionally optimal composition of isochores" [27].

These inverse slight COMT genotype effects (with nonsignificance but more than medium effect size) in normal controls suggested the possibility that individuals with the Met allele might have dopamine levels that are not necessarily more functionally optimal than those of the Val/Val individuals under normal conditions.

The design of safety critical systems frequently necessitates to simultaneously fulfill several logical and numerical constraints as requirements in order to deliver a functionally correct and optimal target system.

Because the clavicle is a non-weight-bearing bone and is functionally expendable, the optimal surgical resection method for GCTs in this area is controversial.

Since protein folds are classified into superfamilies based on common functions and evolutionary relationships, it is likely that the PCAIN-based methodology enables handpicking of an optimal functionally-related template molecule for modeling the structure of the unknown protein, thus contributing significantly towards improving the accuracy of structure prediction.

With the objective to obtain the highest numbers of functionally active Treg with optimal direct alloantigen-specificity, we devised four expansion strategies, employing polyclonal and alloantigen-specific stimulation in two subsequent cycles of Treg expansion (Figure 1).

We report the finding of an optimal layout of functionally graded materials (FGM) towards indentation resistance.