Sentence examples for functionally opposite from inspiring English sources

These findings suggest that the S184 nonphosphorylatable Bax or dephosphorylation of Bax at S184 site may cause a conformational change by exposure of 6A7 epitope that leads to activation of the proapoptotic function of Bax, which is functionally opposite with the mobility shift derived from the phosphomimetic mutation at this site (i.e.S184E; Fig. 1 vs. Fig. 3).

CAAs functions are mainly mediated by leptin and adiponectin, two functionally opposite members of the adipokine family, that seem to play a pivotal role in cancer progression [ 157].

It is possible that the binding ratio of two families of functionally opposite motor proteins (kinesins and dyneins) may determine the movement state of mitochondria and that the bidirectional mitochondrial movement is the result of stochastic tug-of-war of the two families of opposing motor proteins.

The coexistence of functionally opposite marks in immature progenitors and in myelinating cell lines was indicative of a "poised", but inactive or weakly active transcriptional state at the myelin gene loci.

The similar effects of both isoamylase profiles are also surprising as they are expected to be functionally opposite.

However, PPARδ deficiency (as assessed through the PPARδ null mutation) may not necessarily be functionally opposite of ectopic PPARδ activation as it is possible that any alteration in the levels of PPARδ activity, whether a reduction or increase, have different consequences dependant on the genetic background or indeed tissue being studied.

Functionally, miRNAs are opposite to transcription factors, which turn on genes, while miRNAs function as modulators by down-regulating gene expression [7], [48].

In particular, Claudin-1 and Claudin-2, though mediating opposite functionally effects, were induced, while cytoplasmic adapters and Occludin were rather unchanged in relation to controls.

For example, it has been reported that the structure of PRC1 may differ when it is proximal to the TSS versus when it is bound distally; functionally, this results in opposite consequences on gene expression after depletion of PRC1 components [ 36].

As those haplotypes carry CTLA-4 CT60*G and CTLA-4 CT60*alleleses, respectively, each of them having opposite functional effects on CTLA-4 mRNA expression, we just wondered in the discussion how such an association could be functionally explained.

Even with the contrasting differential expression patterns observed among Illumina sequencing data, qPCR and previous report [ 58], for osa-miR397a/b, osa-miR398b, osa-miR408-5p osa-miR408-5p osa-miR408-5pult still points to the opposite, and perhaps functionally significant, expression profiles of these genes between the drosa-miR528-5pt and drought-stillpoints rice varietoes.