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We found that the deactivation of the motor activity of myosin II structurally and functionally only affects the stress fibers, not other actin structures in the cytoplasm and does not significantly affect the motion of beads embedded in the cytoplasm.
Functionally, only cBID and cBIDG94E that cause cristae remodeling but not cBIDKKAA reduced glutamate-supported RCR in DKO mitochondria.
CDK2 has been characterized functionally only human and Drosophila in mammals and its role in Tat-dependent HIV-1 transcription is still unclear [ 27, 28].
It has been suited functionally only in a few species of bacteria, most notably in E. coli, where this gene is part of an operon involved in L-lactate utilisation [ 87].
Functionally, only cell lines bearing mutations in the hotspot helical domain of PIK3CA were sensitive to the drug, independent of other genetic alterations in the PI3K or MAPK signalling pathway.
With the assumption that a high absolute PCC value would reflect a potentially close relation to REGγ functionally, only genes bearing high PCC scores were selected for subsequent studies.
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These kinases are not only functionally but also structurally conserved, consisting of heterotrimeric complexes similar to SNF1 in yeast.
It has previously been noted that the endolysosomal compartments of degenerating neurons are affected not only functionally, but also in terms of appearance, e.g. size, shape, and density [ 9, 28].
Such individual variability in neural circuit elements was hidden under normal conditions, but became functionally relevant only when the system was challenged by injury.
The mixed message comes amidst the freight of a foreign policy featuring drone strikes in Muslim countries, a reluctance to foreclose on indefinite detention that functionally is only aimed at Muslims, and difficulty concluding the war in Afghanistan – all of which have strained relations with American-Muslim communities.
Half of Hispanic and African-American fourth-graders are functionally illiterate; only a quarter of students who take the ACT college assessment exam qualify as college-ready on all four sections; half of community college entrants require remediation to succeed in college classes.
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