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Identifying targets of LDEs is critical to understand how such modifications are functionally implicated in oxidative-stress associated diseases.
Finally, we confirm that Atrx-dependent target genes found to mediate migratory and differentiation phenotypes in mNPCs are similarly misexpressed and functionally implicated in ATRX-mutant human glioma tumors and cell lines.
We identified the PrDs in the viral surface proteins that are involved in the direct contact and fusion of viruses with the host cell membrane, indicating that PrDs may be functionally implicated in these processes as well.
Background & Aims: Carbonic anhydrase (CA) IX is a highly active enzyme with adhesion capacity that is functionally implicated in acid-base balance and intercellular communication.
Interestingly, the planarian EGFRs and ligand show a broad spectrum of expression patterns23,25,30 and are functionally implicated in the regeneration and homeostasis of different organs and cell types, such as the pharynx, the excretory and nervous systems, and the eye pigment cells23,25.
The latter finding suggests that ERCC6 may be functionally implicated in the aetiology of AMD.
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Moreover, the assessment of functionally implicated response predictors in these clinical trials may help to identify the patient subgroup most likely to benefit from treatment with dasatinib.
We asked whether the distribution of OR expression intensities was different in functionally implicated tissues as compared to other tissues.
Functionally implicated residues and motions were extracted in 3 steps from equilibrium simulations of the unphosphorylated state.
Among the functionally implicated eSNV alleles, more than 95% are found in non-conserved regions (phastCons score <0.5), implying as much as 20-fold underestimation of the number of causal ncSNVs that are not found in evolutionarily conserved regions.
AZGP1 has functionally been implicated in lipid metabolism, the regulation of cell cycling and cancer progression.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com