Sentence examples for functionally established from inspiring English sources

It has been suggested that broadly functional genes are more easily duplicated than functionally established ones, and that the modifications that follow the duplications should provide the appearance of new functional specificities.

Once functionally established, epistasis should be evaluated by interaction studies between different susceptibility genes.

Thus, a plethora of functionally established Tol2-based constructs are available.

To ensure effective production of the alterochromide molecules in the E. coli heterologous host, we utilized a functionally established PPTase from the related strain Pseudoalteromonas luteoviolacea 2ta16.

If that were the case, would it be possible to explain, based on sequence analysis, why the chl- fus gene was not successfully transferred and functionally established in a location different of the actual one?

Given that fasting typically increases the plasma level of free fatty acids that are natural ligands of PPARα, and elevated interaction between PGC-1α and HNF4α is a hallmark of fasting adaptation, functionally establishing CAR as a target gene of PPARα and HNF4α provides a novel mechanistic model for CAR in energy homeostasis (Ding et al., 2006).

As the mdx mouse has a defined genetic background for the dystrophic phenotype, it is a very suitable model not only to study pathophysiological mechanisms of DMD but also to functionally establish the benefits of gene therapy strategies [3].

The challenges will then be to systematically assess these proteins functionally, and establish those that are critical members of the functional beta cell surface landscape and thus harbour therapeutic potential.

To test whether 5-LOX−/− fibroblasts are functionally impaired, we established cultures of WT and 5-LOX−/− cardiac fibroblasts.

To accomplish this, we comprehensively searched for articles related to rice functional genomics and established a list of functionally characterized genes.

Based on higher-order shear plate theory and elastic piezoelectric theory, the nonlinear geometric and constitutive relations of the piezoelectric functionally graded plate are established, and then the nonlinear motion equations of the piezoelectric functionally graded plate are obtained through Hamilton's variational principle.