Sentence examples for functionally bound from inspiring English sources

Structural analysis revealed that the siRNA is functionally bound at both ends to RISC.

In the human brain, motor and non-motor areas are functionally bound together to work as a global network both in planning and performing a motor act.

Our results emphasize that despite being functionally bound to a phenotypic trade-off, the common genetic basis of litter size and birth size is comprised of antagonistic as well as parallel genetic variation.

The high overlap in the regulatory networks influenced by Dichaete and SoxN [ 51] might itself lead to selective constraint on binding sites, as mutations affecting sites that can be functionally bound by both TFs would have a greater disruptive effect.

Details of the following validations can be found in Additional File 3. When several genes are functionally bound by the same TF, one might expect that the gene products of these genes are prone to carry similar cellular functions [ 7, 31].

In this study, we demonstrate that curcumin significantly induced Sp1 mRNA and protein that physically and functionally bound to all three Sp1-responsive elements (GC-box) in 5′-proximal region of Prdx6 gene promoter in vitro and in vivo, and that curcumin enhanced Prdx6 transactivation.

These experiments further confirm that Sp1 functionally binds and activates transcriptional activity of Prdx6 promoter.

The data obtained with the w/o cyto CX3CL1 mutant using the dual pipette assay suggest that the CX3CL1 molecule without its cytosolic domain has the same probability to functionally bind the CX3CR1 receptor in the counter-adhesive cell as the native CX3CL1 (Fig. 1F), but that its resistance to radial force is slightly less, likely due to some impaired link to the cytoskeleton (Fig. 1E).

They also demonstrated that Stp1p can functionally bind to the promoter of BAP2 independently of the presence of the functional binding of Leu3p to BAP2 and are synergistic with Leu3p, suggesting the possible masking effect on the knockout event of Leu3p on BAP2.

Whether or not A. americanum putative S19 protein (GBAI01000085, GBAJ01000004, and GBAK01000158) will functionally bind pro-inflammatory cytokines remains to be investigated.

The reconstructed LHC was able to functionally bind Chl a, b and c as well as the carotenoids lutein, fucoxanthin and peridinin in addition to its native zeaxanthin, albeit with some variation in affinity.