These findings, and those reported in the present investigation, suggest that the mammalian epithelial sugar transporter ensemble (e.g. SGLT1, GLUT2, GLUT5) for gastrointestinal absorption of glucose and fructose may be present in crustaceans, but the invertebrate SGLT-like process functionally appears to resemble a Na+/K+-dependent SGLT4 more than a Na+-dependent SGLT1.
These biomarkers suggest that the alveolar barrier function appeared to be functionally restored on post-exposure day 7.
In contrast, the two loss-of-function mutations at Ma1 appear functionally distinct, with families A and B segregating for a small-effect QTL and families C, D, and E segregating for a large-effect QTL.
Functionally, it appears with the first sign of a reflex activity during the second prenatal month, when stimulation by touch of the upper lip evokes a withdrawal response of the head.
Functionally carnosine appears to be pluripotent as there is evidence that it can scavenge reactive oxygen species (ROS) [6] and reactive nitrogen species (RNS) [7], can form adducts with deleterious aldehydes and ketones [8 11] and can act as a metal ion chelator [12] and hydrogen ion buffer [13].
Functionally, it appears that dSmad2 is more similar to Smad3, due to the lack of a 30 amino acids insertion in the MH1 domain present in some isoforms of vertebrate Smad2 that prevent binding to DNA [11], [13], [14].
Henderson's stories largely focus on getting around WHO bureaucracy, often by bypassing it functionally, while appearing to follow it carefully.
The capacity to be functionally compensated appears to vary, in the order non-disease genes > monogenic disease genes > polygenic disease genes (Podder and Ghosh 2011).
Functionally, DISC1 appears to be involved in a multitude of cellular processes, including processes that are critical for both brain development and the activity of the adult central nervous system (CNS) (Brandon & Sawa, 2011).
The fusion of two genes, which interact or are closely functionally linked, appears to decrease the regulational load in the cell, for a particular process [ 1, 2, 8] and may hence be advantageous under specific circumstances.
Functionally it appears that this is in part mediated through cross talk with growth factor receptors and adhesion molecules, such as integrins and cadherins, to promote angiogenesis, tumour cell proliferation and to support formation of the tumour microenvironment.
