Sentence examples for functionally activation from inspiring English sources

Functionally, activation of the EC and persistent neuronal activity in the EC are involved in the process of working memory (Ranganath et al., 2003; Fransen, 2005; McGaughy et al., 2005).

Functionally, activation of Notch2 signaling favors cell death while Notch4 activation was shown to be protective [9].

Functionally, activation of Sytl1 stimulated intracellular trafficking of CXCR4 to the plasma membrane, which in turn led to cell migration toward its ligand, CXCL12.

These observations have suggested the hypothesis that the deleterious effects of either mtDNA- or nuclear-gene mutations could be overcome, at least partially, by increasing the total amount of mitochondria and/or of functionally active "MRC units," via activation of the mitochondrial biogenesis program in critical tissues (Bastin et al., 2008; Wenz et al., 2008).

It has been reported that NF- κB and JNK are functionally interconnected; activation of NF- κB inhibits the activation of JNK and vice versa [ 22].

Functionally, TPL2 activation induces ERK, JNK, and NF-κB signaling pathways in both stimulus- and cell type-specific manners [38], [50].

Functionally, the activation of axonal GABAA receptors has been associated with a reduction in the safety factor of action potential initiation [19] and conduction [46] as well as the regulation of neurotransmitter release [47].

Previous investigations of correlated gains include a recent study in breast cancer [30] where co-amplification of 8p12 and 11q13 was identified and thought to cooperate functionally through activation of independent oncogenic pathways.

To this end, chemotaxis, phagocytosis and reactive oxygen species (ROS) production were assessed in peripheral blood neutrophils, together with membrane expression of CD11b and CD69 – two functionally different activation molecules [ 17].

Thus, TGF-β1 activation functionally restrains ER-α-positive cells from proliferating in adult mammary gland.

Therefore, it seems that the hallmark of regulatory DCs is their ability to functionally inhibit lymphocyte activation rather than their specific phenotype and maturation stage.