Sentence examples for functionality specificity from inspiring English sources

Therefore, one of the well characterized isoforms of the human GalNAc-Ts family, GalNAc-T2, was stably expressed in N. benthamiana and used to demonstrate that mammalian GalNAc-Ts retain their functionality, specificity and localization in plant cells.

Our current model proposes that HATs are differently required, depending on the stage of gene activation, with a high functional specificity in the early gene activation stage and with a less-specific functionality in the later maintenance stage.

After confirming the functionality and specificity of the construct in vitro, transgenic mouse lines were generated by pronuclear DNA microinjection.

The endogenous inhibitors of the MMPs (TIMPs) constitute a set of 4 small molecules with unique functionality and specificity.

Taken together, thioredoxins and glutaredoxins are present in the mitochondria, plastids and cytosol of P. tricornutum and T. pseudonana, although their functionality and specificity is unclear.

Full-size antibodies extracted and purified from plant tissues were tested for functionality and specificity by (i) binding to HER2/neu on the surface of a human mammary gland adenocarcinoma cell line, SK-BR-3, in fluorescence-activated cell sorting assay and (ii) testing the in vitro and in vivo inhibition of HER-2-expressing cancer cell proliferation.

In vitro experiments showed a direct correlation between the extent of decreasing GSH levels and impaired cell viability (Suppl. Fig. 1), proving functionality and specificity of our approach.

To reveal the functionality and specificity of the predicted CBM1 domain, the binding of Cbh1 or CelD was evaluated by a pull-down assay.

Having established functionality and specificity of the sTRAIL variants, we generated adenoviral vectors with expression cassettes containing the TRAIL-R-specific sTRAIL forms.

In this study, we designed and evaluated an HER2-targeted bispecific fusion protein as a model for HER2 imaging to demonstrate the functionality and specificity of the novel hapten and anti-hapten antibody reporter system.

The functionality and specificity of these histone methylation sensors was successfully demonstrated in response to methyltransferase and demethylase inhibitors in cell lines, and noninvasive repetitive bioluminescence imaging in living animals.