Sentence examples for functionality prediction from inspiring English sources
Nevertheless, we believe that these models are a good information source, relevant for vaccine design and functionality prediction.
In an attempt to resolve this issue, we conducted protein functionality prediction by evaluating the similarity of topological properties between the protein and its level-1 direct) level-1 directdirect) neighbors in protein interaction networks (PIN).
For the aliphatic thiol-specific OR2C1 the 11 alleles have similar intermediate-level functionality prediction.
(Since every block instance had not been verified as a cis-element, the 'true' and 'false' concepts in these equations reflected sequence analysis performance rather than functionality prediction).
For missense mutations, functionality prediction was performed with the algorithms PolyPhen [ 21] v1.12 (based on March 2006 releases of UniProt [ 27], NCBI nrdb [ 28], PDB [ 29] and DSSP databases [ 30]) and PANTHER [ 22] (based on PANTHER HMM library v6.0).
We then aligned the putative promoter 1A region found ca. 500 bp upstream the ATG and looked for different criteria enabling functionality prediction, namely, the conservation of the promoter region, the splice donor site and the coding region with bona fide initiation site.
One can easily carry out functionality predictions for any TF of interest based on GO annotations and cis-motif search results.
The p.G613A, however, present in the N-terminal helical bundle of VPS9, is not conserved even in mouse RIN3, and is likely to be a neutral substitution consistent with data from automated functional prediction tools (Functionality score = 1; Table 1).
Amino acid preferences in proteins of different functionality have been utilized before for coarse function prediction from sequence alone (e.g. [ 46]).
They are commonly used for protein function prediction where similar binding patterns imply similar catalytic functionality.
These classification schemes help us understand how disordered protein functionality is defined and could be used to enhance function prediction for disordered protein regions in general.
