Sentence examples for functionality of the receptor from inspiring English sources

Functionality of the receptor was assessed by co-transfection of 293 fibroblast cells with marmoset prolactin receptor cDNA and the Jak2 cDNA, or marmoset prolactin receptor and a Stat5 responsive element linked to the luciferase coding sequence.

The functionality of the receptor was evident by the specific binding of IgE to the FcεRI α-chain.

As it is shown in Figure 7C, activation of Fas by CH11 lead to a higher upregulation of these proteins in the resistant cell line compared to the non-resistant cells, pointing to a change in the functionality of the receptor in cells that have acquired resistance to apoptosis-induction by oxaliplatin.

The functionality of the receptor was also confirmed by the increased phospho-ERK1/2 content following tryptase-induced PAR-2 activation.

The NR1 subunit is essential for the functionality of the receptor, whereas the NR2 subunits determine the biophysiologic properties of the channel, like the conductance and the average time of opening or blocking sensitivity to Mg2+ [ 5].

We indirectly investigated the binding of salmon calcitonin to the calcitonin receptor by examining the levels of intracellular cAMP in isolated chondrocytes and thereby the functionality of the receptor.

To evaluate the functionality of the receptors, we examined IL-8 production by hUCB-MSCs in response to their specific agonists.

Thus, the observed altered expression of EP receptor subtypes in CRC patients compared to non-CRC subjects does not seem to be manifest in the functionality of the receptors in epithelial transport.

Exposure of these individual cells to the promitogenic insulin analogue X10 that activates both the INSR and the IGF1R, resulted in intact downstream signaling cascades in all three cell lines, indicating functionality of the receptors (Fig.  1b).

In Cohorts 3 and 4 of HI and LI rats, we evaluated 5-HT2CR protein and transcript expression in the mPFC to gain insight into the functionality of this receptor as a neuromolecular substrate for impulsive action.

Next, we wanted to know whether blocking MET receptor activation influences the expression and functionality of the CXCR4 receptor.