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Mueller, S.N. & Germain, R.N. Stromal cell contributions to the homeostasis and functionality of the immune system.
Mueller, S. N. & Germain, R. N. Stromal cell contributions to the homeostasis and functionality of the immune system.
Moreover, the age-related decline in the functionality of the immune system (immunosenescence) [5] is characterized by a chronic low-grade inflammatory status (inflammageing) [6] [8].
However, fundamental differences in genomic organization and functionality of the immune system have been found in teleost lineages.
Research in ecologic immunology has shown that the functionality of the immune system has to be considered in an ecologic and evolutionary life-history context.
Furthermore, these genes formulate an important genetic functionality of the immune system, which illustrate the relationship between schizophrenia and autoimmune diseases.
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Sleep is important to the functioning of the immune system.
SNPs alter the phenotype and functionality of proteins in the immune system thereby affecting its function leading to disease.
Nowhere is this level of functionality more needed than in curing disorders of the immune system.
Regarding the deterioration of the immune system's functionality, steroid therapy is a major risk factor as it may be administered either as anti-inflammatory drug in the course of infections or as immunosuppressive treatment during transplantations [ 43- 46].
Classifying interconnected and overlapping components of the immune system into subsets, according to their functionality, such as cellular versus humoral immunity or innate versus adaptive immunity, permit the complex immune system to be dissected into distinct areas.
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