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Better assays are needed to assess proliferative capacity and kinetics of response, breadth and depth of response, functionality of response including both cytolytic and noncytolytic virus suppression activity, and localization of immune responses beyond just the blood compartment.
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Patients who go on to be chronically infected often do not lack a cell-mediated response initially, but there is evidence that the timing, persistence and functionality of the response are insufficient to control HCV [21,48,49].
Critical care outreach teams have the functionality of rapid response teams together with a surveillance function as well as ICU discharge follow-up.
By applying the Rasch model, we explored the unidimensionality of each subscale, the functionality of the response categories, and how well the sample was targeted by the scale.
GM-CSF was also found to both increase the induction of peripheral and mucosal CD4+ and CD8+ T cell responses following PMED DNA vaccination and influence the functionality of those responses.
Simulation tests show a good functionality of controller in response to some inputs to confirm the success of the design.
This has led to a variety of new models, each with a focus on one or more aspects of biophysical reality that might underlie the functionality of grid cell response.
Furthermore, the malaria vaccine candidate AMA1 provides the possibility of assessing functionality of the immune response by a parasite growth inhibition assay.
However, it should be noted that the presence of wild-type p53 does not guarantee functionality of the p53 response and we have not investigated this here.
The overall functionality of the immune response was determined by challenging nBmp2NLStm and wild type mice with systemic Staphylococcus aureus (S. aureus) infection and assessing bacteremia and mouse mortality.
Functionality of T-cell responses in terms of quality or capacity to secrete multiple cytokines has been shown critical in relation to the protection capacity of the T-cell response [27].
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