TCDD has a long-term immunosuppressive-effect on T-helper cell function, which is mediated more likely by a reduced functionality of individual cells rather than by a reduction in absolute cell numbers in the peripheral blood.
This has not been aided by investigations focussing on the functionality of individual tetraspanins, despite evidence for their ability to form and probably function as complexes (Lazo, 2007).
However, little was known about the protein domain architecture, gene expression and the functionality of individual proteins.
As usability testing is best at seeing how people perform specific tasks, it should be used to examine the functionality of individual features and the way they're presented to the intended user.
All 22 Democratic co-sponsors of Protect IP previously voted to protect net neutrality, a policy that prevents corporate telecommunications giants from dictating the accessibility and functionality of individual websites.
The above analysis suggested that age alone does not directly determine the functionality of individual ABGCs.
To what extent is the functionality of individual genomic elements only observable (used) in specific contexts (for example, regulatory networks and mRNAs that are operative only during embryogenesis)?
There are numerous excellent reviews of literatures that define the functionality of individual memory systems of the brains (e.g., Eichenbaum and Cohen, 2001; Tulving, 2002; Boyden et al., 2004; Colombo, 2004; Yin and Knowlton, 2006; Fuster, 2009; Kesner, 2009).
Biologic inference on functionality of individual candidate single nucleotide polymorphisms (SNPs) within genes of interest may be limited and conflicting, and so choosing multiple genes in related pathways is attractive.
PSP coding genes are critically important for functionality of individual synapses and brain as a whole [ 17- 19], therefore we specifically investigated if these genes are enriched among miRNA targets.
