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Oxygen availability is a critical factor in regulating cell viability that ultimately contributes to the normal morphogenesis and functionality of human tissues.
Systematic studies investigating how fibrillar and oligomeric forms of Aβ influence the differentiation and functionality of human stem cells are therefore important.
Obviously, the cell culture conditions have a huge effect on the survival, proliferation, differentiation, and to the functionality of human neural cells.
Evolutionary conservation was previously used to evaluate the functionality of human mtDNA variants within RNA genes Ruiz-Pesini and Wallacee 2006).
Thus, tumor-derived factors in PC are capable of changing the phenotype and functionality of human blood monocytes, converting these cells into immunosuppressive Mo-MDSC.
To assess the functionality of human CCT8L sequences we investigated their expression profiles in comparison to those of human CCT monomers and BBS genes (see additional file 10: Table S4).
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In addition to indirect indicators — such as the functionality of human-specific reagents in methylation and qPCR analysis – the human origin of TER cells was further confirmed by positive immunostaining for human-specific nuclear antigen (Fig. 1.A,C).
Here, we combine a fibrin-based dermal matrix with a biomimetic 'organ-on-chip' system for the development of human skin equivalents that better recapitulate the structure and functionalities of human skin, compared to conventional static culture systems.
Current skin-equivalents do not recapitulate the full functionalities of human skin, and recent efforts have been towards reproduction of 3D architecture of skin, as well as realization of vasculature using microfluidics.
Inspired by the functionalities of human memory, we proposed a distributed network memory management system, termed NetMem, to efficiently store Internet data and extract and utilize traffic semantics in matching and prediction processes.
The RMS that continues to supply replacement interneurons to the rodent OB is weak in humans, possibly reflecting the reduced functionality of the human OB.
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