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However, since only a small number of proteins share motifs B and C, we should be cautious on making assumptions about the functionality of conserved amino acids found in these motifs, as their conservation could be an effect of phylogenetic relatedness and not of evolutionary constraints.
Based on this property, we can further assess functionality of conserved putative novel miRNA.
The analysis of the promoter sequences of these inducible genes reveal differences in the degree of conservation, with NOS-2 showing divergence between rodents and other mammals in the location and functionality of conserved regions containing putative κB and IFN-γ elements.
Thus in our comparisons of the functionality of conserved versus non-conserved sequences, we classified amplicons based on overlap with phastCons Placental Mammal Conserved Elements, 28-way Multiz Alignment intervals [ 41- 43].
The data presented reveal divergence between rodents and other mammals in the location and functionality of conserved regions of the NOS-2 promoter containing NF-κB and IFN-γ response elements.
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In any guise, a Range Rover Sport is equipped with start-stop functionality to conserve fuel; Land Rover's Terrain Response suite of drive settings; and an ability to ford water at a maximum depth of 33.5in.
In addition, we used this assay to dissect the functionality of the highly conserved Ets/Ets/Gata motif in the Scl+19 enhancer, which revealed that the Gata motif is not required for initiation of enhancer activity.
This functionality is conserved across all eukaryotic cells.
That is, their functionality is conserved even when they are embedded in large genetic systems.
Acquisition is the yin of conserving land.
Recycling and source reduction are effective methods of conserving energy, cutting pollution and conserving natural resources.
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