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ATM serine 1981 phosphorylation is associated with ATM kinase activity, and alterations in ATM, MRE11A, RAD50 and NBN may disrupt this biomarker for functionality of ATM kinase activation mechanisms [ 20].
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Interestingly, the evidence that the malfunction of ATM severely impairs glial cell functionality and vascular integrity, has led to the hypothesis that the cerebellar degeneration in A-T is a reflection of a dysfunctional neuro-glio-vascular unit [19].
To further ascribe ATM-dependent functionality of SMAR1-induced cell cycle arrest, SMAR1 overexpressed cells were incubated with KU-55933 before IR.
92 per cent of ATM crime is committed by Romanians.
This acetylation of ATM within its regulatory domain is essential for activating ATM's kinase activity.
ATM is a widespread architecture and it is natural to extend the two-level connection architecture of ATM to the three-level connection architecture of optical-ATM networks.
Performance of ATM networks depends on switch performance and architecture.
"Think about the introduction of ATM machines," she says.
Levels of ATM, p-ATM and p-Chk2 (ATM substrate) were further examined to validate knockdown or inactivation of ATM function.
Acetylation of ATM by the acetyltransferase Tip60 is required for complete activation of ATM [ 56, 57].
GC = gas chromatography (measured value, % of atm); IR = infrared values (measured value, % of atm).
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