The molecular functionality of such structures can no longer be assumed to be optimal, as slightly deleterious mutations may have compromised functional integrity [ 10, 99- 102].
The MEMS synthesis is performed using basic principles with the ultimate goal to guarantee operationability, functionality, compatibility, integrity, controllability and synergy.
Thus, our finding suggested that Cd tolerance S. ramosissima is in certain degree supported by the tolerance of its carbon assimilation enzyme (RuBisCO) and with the high functionality and integrity of the PSII reaction center under Cd excess.
While the use of CPAs such as dimethyl sulfoxide (DMSO) and glycerol mitigate this damage, their toxic nature necessitates removal after thawing and this can adversely affect the functionality and integrity of the recovered cells, tissues or material.
Foils coated with GO, Ag-NPs, and GO-Ag disrupted cell membrane functionality and integrity with significant differences between control groups and the Ag-NPs and GO-Ag groups (Fig. 12).
Foils coated with GO, Ag-NPs, and GO-Ag disrupted cell membrane functionality and integrity with significant differences between the control group and the Ag-NPs and GO-Ag groups.
Therefore, the expression of P27 in both MtΔP27::P27 and MtΔP27::P27-P55 strains confirms the functionality and integrity of the plasmids used to complement the mutant strain.
However, recent insights into pathological changes of RBC functionality and integrity during storage - collectively known as the storage lesion - has drawn attention to the potential negative consequences of pRBC transfusion as it limits the post-transfusion survival of RBCs in vivo [ 3].
We hypothesize that, in Alzheimer's disease, compensatory increases in functional connectivity could help maintain the functionality and structural integrity of secondary atrophy sites, with two main consequences at network level: 1) relative increases of cortical thickness path length, and 2) relative decreases of functional path length (Figure 6).
