How can you tell?" The teacher may help steer student thinking by asking for some elements that might indicate that an item has been intentionally designed by someone or something instead of occurring naturally, such as functionality, evidence of a blueprint, evidence of a maker, repeatability, balance, stylistics or aesthetics, shape, size, etc.
Indeed, we show here that brain reperfusion or glucose administration abolished the effects of mild chronic cerebral hypoperfusion on NVU functionality, evidenced by basal GSK3β tyrosine phosphorylation, nuclear β-catenin abundance and ABCB1 protein levels in brain capillaries.
This implies that between pH 3 and 7, the cysteamine ligand maintained its functionality as evidence from the strongly positive ZP charge which also indicated high colloidal stability.
Although VibraTip™ appears to be easy to use, portable and reliable in its functionality, more evidence is needed on its clinical benefits and economic advantages to support the case for its routine adoption in the NHS.
In addition, the sequence variant does not interfere with Hsp90 functionality as evidenced by the unimpeded growth of the Hsp90rr parasites under RAD.
In addition, the absence of ASM alters neuronal raft composition and functionality as evidenced by the impaired endocytosis and altered distribution of raft components in polarized hippocampal neurons (Galvan et al, 2008).
Endothelium removal or loss of NO-synthase functionality was evidenced when, after treatment with CHAPS or with the NO-synthase inhibitor Nω-nitro l-arginine methylester (l-NAME; 300 μM), the reference endothelium-dependent relaxant agent acetylcholine (ACh; 30 μM) elicited < 5% relaxation after submaximal precontraction with PGF2α (10 μM).
This led to the domination of protein-coding genes in the genomes of microorganisms, although it is likely that RNA never lost its other capacities and functionalities, as evidenced by cis-acting riboswitches and UTRs.
Confirmation or rejection of lncRNA functionality requires experimental evidence that clearly separates the role of the genomic locus from the role of its RNA products.
Based on α-SMA staining and the ratio of desmin to CD31 expression as markers of tumor blood vessel functionality, we found evidence for increased stabilization of colorectal microvessels, but no such change in melanoma vessels.
This case excludes restricted taxonomic functionality and provides additional evidence for functional conservation of syntenic orthologs as defined by "gatekeepers" on a broad phylogenomics range.
