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In addition, defining gene families based on features of demonstrable functionality (domains) should provide a more functionally cohesive grouping compared to assigning genes to families based on often rather arbitrary sequence similarity cut-offs.
Table 3 presents the results of the multiple regression, modelling the effects of providing care on the different functionality domains and the overall disability score.
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Since shorter toxin protein sequences are commonly found and the different types of toxins having different specific functionality, functional domains information are more suitable for identifying the type of bacterial toxins as compared to amino acids composition information in protein sequence.
For each functionality domain, we defined a minimum feature and function set based on consensus reached by our expert panel.
Only two items of the mental health and functionality domain did not comply with the requirements for adequate functioning of rating scale categories.
The Cronbach alpha was 0.91 for the social maladjustment domain and 0.90 for the mental health and functionality domain.
Alternative splicing was shown to affect mostly central IDR of BRCA1 modulating its functionality by removing different functional domains [ 32].
However, the performance of these other information extraction methods still depend on the availability of full-text manuscripts —i.e. if the resource name, functionality or domain is not included in the title or abstract, the complete information about the resource will not be detected.
All these observations support the fact that complex proteins have evolved by extending the functionality of existing domains by insertion, deletion or recombination of domains in the protein repertoire [ 4, 9].
Each pattern addresses a specific functionality of these domains, but some patterns share and integrate information.
Recent studies have suggested these names do not accurately reflect the structures or functionality of the domains.
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CEO of Professional Science Editing for Scientists @ prosciediting.com