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Secondary metabolism varies intensively, even between two closely related taxonomic groups, and the underlining functional variations, such as enzyme activities, often lead to the production of unique compounds.
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To evaluate the functional significance of many variants comprehensively, we assayed 47 variants differentiated by only subtle variations such as missense mutations or one amino acid deletion.
These include information on the minimum set of DNA variations (such as single nucleotide polymorphisms (SNPs), insertion/deletions, or copy number variations) defining the functional gene variant (such as, haplotype or star allele).
Finally, we analyzed the sequence variations (such as domain insertion/deletion) of orthologous proteins to investigate the potentially expressional and/or functional alternations of them between rat and NMR.
Many structural sequence variations, such as small-scale indels, copy-number variations and large chromosomal rearrangements have been identified16,17.
These in turn trigger physiological variations such as elongation growth, respiration, and moisture absorption.
There have also been variations such as "Loreline" and "Laurelyne".
It has variations such as egg or milk Appam.
Many variations, such as prepared guitar, have followed.
There are very fine daiquiri variations, such as Papa's own Hemingway Daiquiri.
Other variations, such as omission of vowels, are also common.
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