Furthermore, the putative functional variant or variants in these loci mostly remain under investigation.
It does this by creating the world's first comprehensive functional variant database solely dedicated to resolving variants of unknown significance (VUS) in genetic tests.
This functional variant, which is a major determinant of HDL-C levels, may have contributed to the adaptive evolution of Native American populations (Acuña-Alonzo et al. 2010).
A functional variant may nevertheless fail to be transmitted because human designers lack clairvoyance (Mesoudi et al. 2004; Nelson 2007; Mesoudi 2008).
The class of functions defined by \(\Sigma_1\ -formulas which are provably total in \Sigma_1\ -formulas) corresponds to a functional variant of this hierarchy (Cook and Nguyen 2010).
First, it is not known whether we have identified the functional variant, or just a marker in LD with the functional variant.
Assuming the same functional variant in the Swedish and the Finnish samples, the two samples would assist in narrowing the interval of that functional variant (Fig. 2C).
They identified a functional variant (rs3758539) in the promoter of RBP4 associated with type 2 diabetes.
The T102C polymorphism might be in linkage disequilibrium with the true functional variant [13].
It could be that these variants tag some nearby functional variant.
This process of defining the functional variant will by itself de-emphasize the broad framework of race/ethnicity.
