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Plasschaert, R. N. et al. CTCF binding site sequence differences are associated with unique regulatory and functional trends during embryonic stem cell differentiation.
However, an emerging literature exploring functional patterns using global fisheries datasets is supporting broad-scale investigation of functional trends through time and across space9.
This knowledge is critical because it explores the need for robust reconstruction of underreported elements of global fisheries to understand functional trends and support ecosystem-based fisheries management.
The functional roles of species may be described using broad functional groups, or using more detailed information on a range of life-history, ecological and behavioural traits2, 5. We explored functional trends using both approaches.
But to date there has been no exploration of the impact of unreported catches, such as the often overlooked multi-species subsistence and artisanal fisheries (hereafter termed 'small-scale' 22, on broad-scale functional trends.
G. Alterovitz, T. Muso, P. Malalur, and M. F. Ramoni, "A Systematic Approach to Quantifying Evolutionary Functional Trends Across the Universal Tree of Life," Proceedings of the IEEE 7th International Symposium on Bioinformatics and Bioengineering (BIBE), 2007.
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The "utility" music he wrote for children's games, youth groups, brass bands, radio plays, and other practical purposes reflected a functional trend in the culture of postwar Germany.
To elucidate the biological significance we used the DAVID annotation clustering tool and found a parallel reversed functional trend.
The –log (p-value) scale differs between Figures 2C and 3C due to the number of miRNAs used for IPA analysis (i.e. 13 vs. 6), but functional trend analysis shows that miRNAs associated with inflammatory disease appear to be approximately the same for both U-87 astrocytoma cells and primary astrocytes (compare Figure 2C and Figure 3C).
Enrichment analysis can be implemented with an ontology or an annotation repository, such as Pfam domains and Swiss-Prot annotations, to understand the functional trend of biological phenomena.
We found that the 10 putative transferred genes were all enzymes, which suggested a strong functional trend among these HGTs in B. mori.
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