Sentence examples for functional tests in from inspiring English sources

This has immediate practical consequences: e.g. since there are three types of methylation codes, pan-species conclusions about the potential function of DNA methylation can only be drawn within the type (e.g. functional tests in vertebrates with high gene body methylation cannot be used to conclude on methylation function in mosaic type mollusks).

However, very few duplicated gene families in vertebrate species have been analyzed by functional tests in vivo.

Then the functional tests in the simulation environment can be ordered with the test prioritization based on the enhanced k-means algorithms.

In practice, the success of the simulation-based verification highly depends on the quality of functional tests in use which is usually evaluated by coverage metrics.

Secondly, Monocytes, granulocytes, dendritic cells and lymphocytes function were assessed at day 0, day 1 and day 3 using flow cytometry and functional tests in patients receiving ECLS and compared to patients with cardiogenic shock without ECLS.

Our findings expand the allelic repertoire of SEDT and show how prior filtering of the morbid human genome informed by inheritance pattern and phenotype, when combined with appropriate functional tests in patient-derived cells, can expedite discovery, overcome issues of missing data and help interpret variants of unknown significance.

The fact that some of ARUP's clients perform the functional tests in-house indicates a likely bias in our full data set.

Functional testing, in turn, investigates whether the software functionalities of the final product are responding/behaving as expected without using knowledge about the code [3].

More importantly, functional testing in mouse transgenic assays has validated the predicted enhancer function of a large proportion of these predicted elements.

Thus, integrating human genetics and functional testing in neuronal lineage induction is a promising approach for discovering candidate lncRNAs involved in neurodevelopmental diseases.

This review describes the basic principles of functional testing in mouse, summarizes the contributions these studies have made to our understanding of enhancer biology, and describes limitations and future outlook of in vivo mouse enhancer studies.