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The immediate neighbors of a miRNA tend to be synergistic, which are functional synergistic partners.
In line with this possibility, Parp1 /– Parp3–/– mice show increased sensitivity toward radiation-induced DNA damage as compared to either single disruption, supporting a functional synergistic crosstalk between both enzymes for DNA damage responses and genome maintenance.
This result suggests that the functional synergistic regulations of the crosstalk motifs could be based on the PPIs between regulated private target genes, highlighting the functional features of the crosstalk motifs.
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Herein, a multi-functional synergistic photoelectrocatalytic (PEC) interface is employed to realize enhanced PEC CO2 reduction by using intrinsic Au doped TiO2 as the light harvester, nanotube photonic crystal (NTPC) as optical channels and Cu nanoparticles (NPs) as CO2 electrocatalyst.
Although function prediction of insect SPs is a very challenging task, the co-existence of these two functional domains suggests synergistic function for them in immune responses [ 7, 44, 45].
The main contribution of this paper is the proposed biomimetic cocontraction control strategy, which co-activates the antagonistic muscle pairs as a synergistic functional unit.
So, the construction of other NGO-encapsulated functional nanomaterials for synergistic therapy of malignancy deserves our further efforts.
A key step in the method is the identification of gene-gene functional interactions as synergistic events; these events are determined not only by gene expression data but also by prognosis.
Thus, a synergistic functional effect of both factors was evident in seedlings.
The similar expression patterns of duplicated genes or genes from the same PIN group indicate functional redundancy, while synergistic expression of GmPINs from different group suggests functional complementation.
We could thus show that, in vegetative organs of seedlings, HaHSFA9 and HaHSFA4a showed synergistic functional effects on tolerance to severe dehydration and to drastic oxidative stress.
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