Sentence examples for functional strands of from inspiring English sources
Once they're coded, Church can assemble the letters into biologically viable, functional strands of DNA.
The New Yorker explained that to place the coded version of Wikipedia into functional strands of DNA, Davis has to use a type of bacteria that can lodge its own genome through plant cell walls.
The functional strand of the mature miRNA is loaded together with Argonaute (Ago2) proteins into RISC complex [4].
Moreover, the functional strand of mature miRNA loads onto the RNA-induced silencing complex (RISC) to suppress the expression of specific mRNA targets by directing mRNA degradation or translational repression [ 17, 18].
Existing approaches fall short in predicting the location of mature miRNAs but also in finding the functional strand(s) of miRNA precursors.
In addition, the expression of both the functional strands 3'-end (miR-9) and 5'-end (miR9*) of the miRNA hsa-miR-9* has been recently described to be induced by c-Myc [17], [18].
Moreover, our tool can avoid the problem of identifying the functional strand in novel miRNA precursors, where the performance accuracy of all compared tools is very poor, by providing as computational truth the miRNA:miRNA* duplex while maintaining the same high accuracy in terms of start nucleotide prediction.
It should be noted that prediction of the miRNA:miRNA* duplex is an important advantage of MatureBayes as it avoids the problem of identifying the functional strand when this is not known a priori while maintaining a very similar prediction accuracy for the start position of either the mature miRNA or its miRNA*.
Prediction of strand-specific miRNA candidates is more suitable for cases where the functional strand is known a priori, while prediction of the miRNA:miRNA* duplex can be applied in all cases.
One miRNA was predicted to be functional for both strands of the mature/star duplex in human.
Yeasts normally consume sugar and excrete carbon dioxide and alcohols, but new gene-editing technologies such as CRISPR have made it much easier and faster to insert strands of functional DNA from other organisms into the yeast genome, transforming its metabolism.
