Sentence examples for functional strand from inspiring English sources
Sun et al. (2009) revealed that sequence variations in mature miRNAs and around the processing sites have profound influence on the mature miRNAs generation, processing and functional strand selection.
The functional strand of the mature miRNA is loaded together with Argonaute (Ago2) proteins into RISC complex [4].
Existing approaches fall short in predicting the location of mature miRNAs but also in finding the functional strand(s) of miRNA precursors.
Prediction of strand-specific miRNA candidates is more suitable for cases where the functional strand is known a priori, while prediction of the miRNA:miRNA* duplex can be applied in all cases.
For duplex prediction, the classifier's performance is assessed assuming that the actual mature miRNA corresponds to either the predicted mature miRNA or the predicted mature miRNA*, without explicitly specifying the functional strand.
As evident from the above findings, MatureBayes significantly outperforms ProMiR in terms of predicting the start position of mature miRNA(s) within a given precursor, especially when the functional strand is known a priori.
Once they're coded, Church can assemble the letters into biologically viable, functional strands of DNA.
The New Yorker explained that to place the coded version of Wikipedia into functional strands of DNA, Davis has to use a type of bacteria that can lodge its own genome through plant cell walls.
Figure 4A shows the average distance distribution of the top scoring candidates from the actual mature miRNAs (estimated over the known functional strands) during the 10-fold cross validation procedure.
In addition, the expression of both the functional strands 3'-end (miR-9) and 5'-end (miR9*) of the miRNA hsa-miR-9* has been recently described to be induced by c-Myc [17], [18].
If this has been successful, two blades in the tool cut precisely into the cable at the right depth to slice the insulation over the wire, but not the functional strands.
