Sentence examples for functional spots from inspiring English sources

However, due to the fact that several of the fsr-genes had been excluded from the data analysis as a result of the number of functional spots in the latter strain (see Materials and methods), the expression of fsrB was verified by real time quantitative PCR (QPCR; Figure S3).

At the same time, models generalized for the entire human proteome may not perform well with CYPs, as these enzymes have highly variable regions – substrate recognition sites (SRSs) – that cannot be recognized as critical functional spots by evolutionary based methods.

Cao and colleagues reported that hepatocytes sequester or pre-recruit structural and enzymatic components of the clathrin-based endocytic machinery to functional hot spots on the basal membrane (Cao et al., 2011).

Functional "hot-spot" residues are enriched among the predicted interface residues, rendering the method predestined for macromolecular binding site identification and drug design studies aiming at modulating protein-protein interaction that might influence protein function.

Besides the functional hot-spots, mutational mapping also reveals high-risk segments on the β-mannosidase protein sequence.

Based on the proximity of these mutations to the enzyme active site and their co-location from different organisms, we have detected functional hot-spots for mutations likely to be involved in -mannosidosis across the four species.

On the other hand, the basal ppGpp level mainly results from the balanced synthesis and hydrolysis activities of the bi-functional enzyme SpoT, which acts as growth rate sensor.

These proteins can be classified into three functional subgroups: redox homeostasis (spots 26-41), signal transduction (spots 42-45) and cell rescue/defense (spots 47-50) (Table S1 and Figure S2B).

Among the 54 identities, 53 are deposited in the current database as putative functional proteins, whereas spot 54 is a hypothetical rice protein with unknown function.

Additionally, it's giving more training to patent examiners to spot "functional claims," which assert intellectual ownership over the idea of an invention rather than its specific application of an idea.

One extension of MRI called functional MRI can spot which brain areas are most active, but until now there hasn't been a high-resolution method for detecting enzyme activity--essentially a measure of what genes are turned on inside a cell.