Sentence examples for functional spindle from inspiring English sources

First, the assembly of a functional spindle is critical for accurate chromosome segregation.

The assembly of a functional spindle is critical for accurate chromosome segregation.

The limiting factors that govern the kinetics of microtubule assembly and organization into a functional spindle during meiosis I remain to be identified.

Alteration of Ran-GTP levels impairs meiosis II spindle assembly but does not prevent the formation of a functional spindle during meiosis I.

This resulted in rapid degradation of Cyclin B1 (Fig. 3A) and 4N DNA containing post-mitotic cells (Fig. 3B, C), as cytokinesis fails in the absence of a functional spindle.

Coalescence of supernumerary centrosomes into two functional spindle poles was observed in all samples with enlarged centrosomes.

However, additional pathways, such as those mediated by chromatin and augmin, are involved in the establishment of functional spindles.

Recent studies suggest that recruitment of a single telomere tract or centromere to the SPB is sufficient to confer functional spindles [ 13, 14].

GRASP65-depleted HeLa cells have also been reported to display multiple, disorganized and non-functional spindle poles and their chromosomes do not align properly on the metaphase plate.

The time-lapse studies indicated that when initiated, anaphase proceeded normally in some PIASγ-depleted cells, indicating a functional mitotic spindle and motors.

Success of meiotic division relies on the assembly of a functional acentrosomal spindle (Kaláb et al., 2011; Dumont et al., 2007).