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Thus, the expansion of V2RA1-5 genes in muroid species probably required a more subtle functional specificity for the coexpressing V2RC.
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In order to maintain good functional specificity for shared functions, without reducing the population of the resulting groups to a trivial number, groups were defined by the lowest internal node that achieved the minimum size threshold.
This may reveal novel functional specificities for these genes.
Besides the functional specificity for methanogenesis, it can be used to infer phylogeny, as the topologies of mcr A/mrt A and ribosomal DNA phylogenetic trees are almost identical [55], and resolution to the species level is possible.
Despite earlier preconceived views of functional redundancy, most of the experimental evidence supports the notion of functional specificity for each Ras family member.
Therefore the amino acid sequences, length and conformation of the loops play important role in their functional specificity (for reviews see [ 53, 55].
The anatomical distribution together with the degree and timing of contrast binding may add further functional specificity for vascular pathological processes under evaluation.
This refocusing has already started to generate a new conceptual framework, which potentially will lead to improved functional specificity for behavior therapy.
In order to determine whether there is any functional specificity for Dis3-mediated regulation during development, we performed GO analysis on those RNAs that were 5-fold increased or decreased in Dis3KD samples.
Alignment positions, accounting for such functional specificity of the three enzymes in L. major were mapped and analyzed for their conservation.
The in vivo roles of common accessory subunits are less well-characterized, but evidence to date suggests that they are important for the functional specificity of the complexes.
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