Exact(44)
However, several recent studies (reviewed in [11]) pinpointed exquisite differences among Hsp70 orthologs suggesting that while they share redundant house-keeping functions, they may exhibit functional specificities that have yet to be fully deciphered.
In addition, functionally related gene families often demonstrate similar evolutionary pressures, functional specificities, because natural selection tends to retain functionally complementary gene gains and losses on these gene families (Fryxell 1996; Pazos and Valencia 2008).
Analyses of the organization of the encoded proteins point out specific molecular signatures, indicative of functional specificities for Snail, ScratchA and ScratchB proteins.
This variety may be reflected in their functional specificities; some of them are water-specific channels but some others are also permeable to other molecules, such as glycerol, CO2, boron and small organic solutes (Henzler and Steudle, 2000; Chaumont et al., 2005).
First, the locally conserved regions, that reflect functional specificities or that modulate a protein's function in a given cellular context,are less well aligned.
Functionally related genes often show similar responses to evolutionary pressures, functional specificities, and phylogenetic tree topologies (Fryxell 1996; Pazos and Valencia 2008).
Similar(16)
It is possible that their functional specificity is derived, at least in part, through specific temporal and spatial expression patterns.
The study of ELK functional specificity also sheds light on EPK evolution and functions.
Implementing more powerful systems implies greater functional specificity, which requires elicitation and capture of increasingly detailed and complex domain-specific semantics and knowledge.
These features provide potentially improved cellular, and hence functional, specificity.
Functional specificity of proteins is assumed to be conserved among orthologs and is different among paralogs.
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