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Both strongly influence the description of the emotional and functional situation by the patient, yet we were not able to prove a relation to the wish for CRS.
Overall, these data support the notion of profound plastic alteration of the corticostriatal connection after DA depletion and L-dopa treatment and further suggest that the apparent normalization in the number of dendritic spines is actually not normalization but reflects the establishment of a different functional situation.
Between 1 and 3 years after admission, approximately 25% of patients improved their functional situation.
30, 31 Furthermore, all patients should receive an individualized rehabilitation program to achieve an optimum functional situation.
The analysis will be focused on the proportion of patients who are recovered to a normal functional situation at the short and long term.
Our interest in this study was to study independent individuals against those presenting some degree of dependence, thus functional situation is classified into two categories.
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Kingma argues that Boorse's Biostatistical theory cannot capture statistically unusual yet functional situations, and concludes that we need to appeal to situation-specific functions.
Synaptic plasticity was compared in two different functional situations of the cortical network: in silent slices (without spontaneous activity) versus in active (oscillatory) slices (Fig. 1A; see Methods).
The primary outcome is the level of disability assessed using the patient specific functional scale (PSFS) which links the perceived pain to functional situations and is measured before treatment and at 6 and 12 months follow-up.
Propensity scores, or the likelihood to be in the treatment condition or control condition, will be estimated with the following (pre-fracture) variables: age, gender, marital status, living situation, functional status, co morbidity, cognitive function, number of medications, need for home care, need for day care.
On the functional level, the situation looks quite different: a reversion of function is thousands times less probable than its damage.
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