Surprisingly, sites within the prepropeptide region were also implicated as being subject to significant positive selection, suggesting previously unappreciated functional significance for this region.
Most low-abundance 'background' Symbiodinium spp. are transitory and have minimal functional significance for symbiotic corals.
A method of defining "packages" of maternal stimulation and their functional significance for the infant.
These results identify functional significance for neuronal MT stability and suggest a mechanism for cellular dysfunction in dynein-linked disease.
This conservation may have functional significance for PfEMP1 folding, transport, or binding activity.
The characterisation of EmTFP250 adds to the expanding apicomplexan TRAP family and suggests a functional significance for the protein.
It is also unclear whether actin is actively exchanged between the nucleus and the cytoplasm, and whether this connection has any functional significance for the cell.
We have, for the first time, identified a proneural gene-expression profile in basal cells, but the functional significance for these genes in regulating the basal cell properties remains unknown.
Available data suggest that divergent N-terminal domains can influence AMPD isoform behavior, but the functional significance for additional divergence within each enzyme is unknown.
Here, we show using the HSPA5 inhibitor - epigallocatechin gallate (EGCG) that the chaperone is essential for virus infection, thereby demonstrating a functional significance for the association.
"I am delighted," said Dr. John Allan Hobson, a professor of psychiatry at Harvard and the director of the Laboratory of Neurophysiology at the Massachusetts Mental Health Center in Boston, "because it suggests that, as we have long suspected, sleep has a lot of functional significance for learning and memory".
