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In contrast, the monocyte-specific functional signature comprised ribosomal genes enriched in ribosomal-related functions, such as translational elongation.
Following the idea that a way of functioning of lincRNAs relies on their structures, this result could be a functional signature to infer a putative mechanism of action shared by HOTAIR and ANRIL.
Identification of a unique TGF-ß-dependent molecular and functional signature in microglia.
Corrigendum: Identification of a unique TGF-ß-dependent molecular and functional signature in microglia.
Butovsky, O. et al. Identification of a unique TGF-β-dependent molecular and functional signature in microglia.
Potts, M. B. et al. Using functional signature ontology (FUSION) to identify mechanisms of action for natural products.
Similar(16)
Moreover, several proteomic and functional signatures were biofluid-specific.
Pantaleo, G. & Harari, A. Functional signatures in antiviral T-cell immunity for monitoring virus-associated diseases.
We compared transcriptional, metabolic and functional signatures of intratumoral CD8+ T lymphocyte populations with high (PD-1T), intermediate (PD-1N) and no PD-1 expression (PD-1–) from non-small-cell lung cancer patients.
In this review, the key functional signatures of the intervertebral disc are discussed and used to propose a series of native tissue benchmarks to guide the development of engineered replacement tissues.
Strikingly, the two assigned gene sets have very different functional signatures.
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