Sentence examples for functional signalling from inspiring English sources

It is possible, therefore, that NRP1 antagonists and siRNAs could indirectly affect tumour cell function by impairing functional signalling mediated via other receptors such as c-Met.

Such co-operativity occurs during assembly of the T cell signalling complex on the Linker for activation of T-cells family member 1 (LAT) scaffold protein, which contains multiple SH2 domain-binding motifs that, upon phosphorylation, recruit a variety of signalling proteins through their respective SH2 domains to build a functional signalling complex [ 88].

RhCD25 was characterized for expression by flow cytometric analyses, ELISA, Western blotting, functional signalling, and biological assays in comparison to HuCD25.

The acquired proteomic signature was compared and GO-STRING analysis was subsequently performed to illustrate the activated functional signalling networks.

To overcome this problem, we decided to develop a strategy that would allow us to identify interacting molecules and functional signalling pathways using genetic approaches.

As a fraction of PDE4D7 is targeted to the sub-plasma membrane, we wished to evaluate whether it had a role in regulating cAMP concentration at this locale as a functional signalling compartment.

It is well known that inflow effects make some contribution to the functional signal change [16].

Here we showed that TSCA can successfully separate functional signal components from other signals referred to as noise.

Thus, modeling functional signal changes is non-trivial and exploratory data analysis (EDA) may be rather useful.

Such a lack of spatial concordance between morphological and functional signal would in turn lead to uncontrollable errors of the PVE correction.

In the seven-helix G protein-coupled receptors, exemplified by the rhodopsins, collective helix motions serve to activate the functional signaling.