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Further, E-Syt2 loss or overexpression inhibits receptor endocytosis and functional signal transduction via the ERK pathway, suggesting that PAK1 might functionally cooperate with E-Syt2 in mediating FGF signalling.
Here we showed that TSCA can successfully separate functional signal components from other signals referred to as noise.
Thus, modeling functional signal changes is non-trivial and exploratory data analysis (EDA) may be rather useful.
Perfusion-based functional magnetic resonance imaging (fMRI) using arterial spin labeling (ASL) methods has the potential to provide better localization of the functional signal to the sites of neural activity compared to blood oxygenation level-dependent (BOLD) contrast fMRI.
Thus, the functional signal induced by membrane translocation of the enzymatic toxin-subunit is magnified tremendously over the signal that can be obtained by direct measurement of the mass of translocated protein.
Expression in a transformed human trabecular cell line or in Crandall feline kidney cells showed cat myocilin was secreted from these cells, similar to human myocilin, suggesting cat myocilin contains a functional signal peptide sequence.
It is well known that inflow effects make some contribution to the functional signal change [16].
When computed for biological objects, the values of a shape characterizer are largely independent of homology interpretations and often contain a strong ecological and functional signal.
Physiological interactions with the axis hypothalamus-hypophysis as well as ovarian internal functional signal are also critically reviewed to explain the abortive development of follicles before the beginning of the ovarian cycle.
Such a lack of spatial concordance between morphological and functional signal would in turn lead to uncontrollable errors of the PVE correction.
The hydrophobic N-terminal sequence of carboxylesterases shows variability but all contains a functional signal peptide that directs the carboxylesterase protein expression to the lumen of the endoplasmic reticulum (ER) (Potter et al., 1998).
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