Although assays claiming to be highly sensitive state a functional sensitivity ≤0.1 μg/l, heterogeneity in assay reactivity may lead to differences in clinical performance.
This assay is highly specific and highly sensitive and has a functional sensitivity of 1.5 pg/ml [ 26].
Serum Tg was measured using a highly sensitive assay with a functional sensitivity of 0.1 μg/l.
Both are fully automated, sensitive, quantitative PCT assays with functional sensitivity of 0.06 ng/mL.
More recently, novel highly sensitive Tg assays (with a functional sensitivity ≤0.1 μg/l) have been developed and are commercially available.
Serum estradiol was determined by an ultra- sensitive extraction radioimmunoassay with detection limit 4 pmol/L and functional sensitivity 6 pmol/L.
Takada, K. & Jameson, S.C. Self-class I MHC molecules support survival of naive CD8 T cells, but depress their functional sensitivity through regulation of CD8 expression levels.
Functional sensitivity could be an optional threshold value to rule out the presence of circulating CtnI.
A coarse categorization could potentially produce low functional sensitivity since FEs would be likely represented by many species, while a fine categorization would lead to the opposite, a high sensitivity with many FEs having only one species.
Previously established response components were successfully grouped based on proximity to the localiser, which characterised location, latency and functional sensitivity.
Variational method (VM) is employed to derive the co-state equations, boundary (transversality) conditions, and functional sensitivity derivatives.
