Sentence examples for functional screenings from inspiring English sources

Functional screenings based on the gain-of-function approach proved extremely valuable in the identification of novel genes involved in key processes related to cancer onset and progression, such as neoplastic transformation, resistance to apoptosis, or escape from senescence [ 1- 3].

One obvious strategy would be to scale up functional screenings by the use of multiple hosts and screening methods in parallel (e.g. Craig et al. 2010).

Functional screenings recently performed in genetically tractable organisms have also unveiled various aspects of CDDP resistance.

Considering that P. putida does not intrinsically produce antibiotics but exhibits extraordinary tolerance to producing such compounds, it may prove especially useful in functional screenings for novel antimicrobials.

Specific detection of almost 1700 murine transcripts at this MOI further confirmed the efficiency of retroviral expression libraries as a tool for functional screenings [ 2].

Due to the complexity and diversity of miRNA-mRNA target interactions, functional screenings using biological methods are very labor-intensive and time-consuming.

It seems to be the relatively narrow-range expression machinery present in E. coli which is preventing an effective match on the individual insert level, leading to the current expression bottlenecks that are often encountered in functional metagenomic screenings.

Ten different microbial habitats (six terrestrial and four aquatic ones) were selected for functional and genetic screenings of the chitinolytic bacterial communities.

The 'screening tests' section included papers on functional movement screen (0 articles identified), questionnaire (1) and isokinetic muscle testing (4).

Tissue-engineered skin equivalents based on primary isolated fibroblasts and keratinocytes have been shown to be useful tools for functional in vitro tests, including toxicological screenings and drug development.

We demonstrate how CBS can be particularly useful for characterizing functional sequences and conducting in silico regulatory screenings of target genes reported in high-throughput expression experiments.