To investigate resting-state functional connectivity in salience (SN), sensorimotor (SMN) and default mode networks (DMN) during the early phase of pituitary adenylate cyclase-activating polypeptide-38 (PACAP38 -induced migraine attacks.
However, to our knowledge no evidence exists proving graded prefrontal cortical NE release induced also by aversive stimuli or, most importantly, the functional role of salience-dependent graded prefrontal NE outflow for behavioral outcomes.
Finally, we apply BSFA to elucidate the dynamic functional organization of the salience, central-executive, and default mode networks three core neurocognitive systems with central role in cognitive and affective information processing (Menon, 2011).
van Tol et al. [ 13] reported decreased functional connectivity of the salience network with the medial prefrontal cortex, ventrolateral prefrontal cortex, and ventral striatum.
AIC displayed increased functional connections with (other) salience network structures (primary somatosensory cortex) and with oculomotor areas (intraparietal sulcus) during error awareness, suggesting coordinated activity of AIC with distant brain regions presumably in an effort to amplify the neural salience-signal of the detected error and to preset task-relevant oculomotor structures.
Balthazar and colleagues [ 67] reported that the NPI 'hyperactivity factor' (including agitation) was associated with greater resting-state functional connectivity in the anterior salience network, particularly in right anterior cingulate and insula.
Employing an attentional blink paradigm, in conjunction with functional magnetic resonance imaging, we manipulated the salience of the second of 2 face target stimuli (T2), by varying emotionality.
Here, we used a novel within-subject psychopharmacological and combined functional neuroimaging paradigm, investigating the interaction between hedonic salience, dopamine, and response set shifting, distinct from effects on action learning or motor execution.
Recent functional connectivity studies seem to suggest that this salience network is crucial for balancing the engagement of task-related, rest-related activity and ongoing activity in the human brain.
Blue symbols denote the TvD function for the cued high axial salience condition; magenta symbols, the cued low axial salience condition; green symbols, the non-cued high axial salience condition; and red symbols, the non-cued low axial salience condition.
