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Herein, we provide evidence that CB2 receptors in the thalamus play a functional role in the modulation of responses of neurons in the ventral posterior nucleus (VPL) of the thalamus in neuropathic, but not sham-operated, rats.
To test whether regulation of tumour Brms1 plays a functional role in the modulation of tumour metastasis in response to systemic SK1/S1P signalling, we first examined the consequences of the overexpression of Brms1 in MB49 cells for lung metastasis in WT mice.
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Although future work will tell whether mutations in the Class III PI3K pathway underlie a fraction of human AVM, our study unquestionably demonstrates that the modulation of Vps15/Vps34 expression has a direct functional role in the development of AVM.
Our findings in human patient cells and animal model open the possibility that the modulation of Vps15/Vps34 signalling has an important functional role in the development of AVMs and lysosomal storage diseases.
Central α1-adrenoceptors: their role in the modulation of attention and memory formation.
The endocannabinoid system may play a role in the modulation of TRPV1 activation [18].
Among these proteins, lipocalins play a major role in the modulation of the inflammatory response.
This study demonstrates that HDAC6 plays an important role in the modulation of mitochondrial transport.
Environmental conditions may therefore have a crucial role in the modulation of neurogenesis during aging in rodents since like in young rodents experience, the stimulation of neurogenesis and improved functional outcomes may be causally linked in aged brains as well.
In recent years, its role in the modulation of inflammation has become increasingly apparent.
It suggests that endostatin plays a role in the modulation of TBI independent of VEGF.
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